The 2011 Nobel prize winners in science (physics, medicine and chemistry)
There were those who sought to the stars and their eyes trying to catch hold of supernovae afar… there were those who sought within their own body, their eyes and mind trying to understand the workings of the immunity system … and then there was one who changed the rulebooks of crystallography… And they are none other than the Nobel prize winners of 2011...
Looking out into the night sky, and trying to solve the mysteries of birth and death, of seeking the arrow of time and predicting our fate. Would we collapse into singularity or would we die out with universe expansion into cold state, or would we continue to enjoy the pleasures of today, in the steady state of a flat universe ? We knew that the universe was growing, after Henrietta Swan Leavitt’s study on the redshift pattern. But what would be our fate was the question… Most cosmologists were happy to believe in the most simple and mathematically elegant Universe: a flat one, where the expansion is believed to decline, and we‘d reach an equilibrium to stay on for eternity. Saul Perlmutter, Brian P. Schmidt, and Adam G. Riess set out to confirm the same only to be startled by discovering that truth wasn’t what they thought, rather the universe was accelerating. Einstein’s concept of cosmological constant was now revived, a term which explained the concept of non-static accelerating universe, a term, which was in dark shadows of rejection in the past. But after the Nobel Laureates’ discovery, things took a 180 degree turn as to the understanding of the universe. They had proceeded to study the universe at cosmic scale, to look more into the past, and go a step beyond Henrietta’s work. And thus, they set out to study supernovae (massive star explosion) where they accounted 50 distant supernovae whose light turned out to be weaker than expected, contrary to what they had envisioned. If cosmic expansion had been losing speed, the supernovae should’ve appeared brighter. But, the supernovae were fading as they were carried faster and faster away, embedded in their galaxies, which concluded that universe is not slowing down – quite to the contrary, it is accelerating. The reason for such a scenario is due to, the dark energy, which is estimated to be 71.3 % of the universe, that forces the expansion and it isn’t a constant quantity, as the universe is accelerating. But what is dark energy is a question, no physicist has an answer to, yet. And yes, we await those who can shed more light on this darkness…
Moving on to the men of honour in medicine :: Bruce A. Beutler, Jules A. Hoffmann and Ralph M. Steinman, have changed the way we think so as to fight against pathogens, by discovering the workings of our own immune system. Bruce Beutler and Jules Hoffmann discovered receptor proteins that can recognize such microorganisms and activate innate immunity (the first step in the body’s immune response). Ralph Steinman discovered the dendritic cells of the immune system and their unique capacity to activate and regulate adaptive immunity (the later stage of the immune response) during which microorganisms are cleared from the body. It is now known, what triggers the immune system response, and what steps we can take to fight against diseases such as cancer and inflammatory diseases. The detailed study of Toll gene has lead to understanding as to why the immune system reacts the way it does, and what changes can be made while avoiding an attack on the body’s own endogenous molecules. Signals arising from the innate immune response and sensed by dendritic cells were shown to control T cell activation, thus the interlink between the innate and adaptive immune system, has opened new doorways of research into development of new vaccines and cures to fight pathogens.
Now, coming to the man, who changed the rulebooks of crystallography, who was faced with complete opposition and even ridiculed for what he had discovered, and also asked to leave the research group by his boss for his claims. He is none other than Nobel Laureate (2011) Dan Shechtman. His article was rejected by Journal of Applied Physics. But tables turned, when he met Cahn, Gratias and his research work then got published in November, 1984, in Physical Review letters. Dan Shechtman and his discovery of quasicrystals changed the very basic concept of crystallography. According to the textbooks, five-fold symmetry wasn’t possible, as the atoms would lie at unequal distances and non-repetitive patterns, the same applies to seven fold or higher symmetries. But what Shechtman saw through his electron microscope was a ten-fold symmetry with atoms aligned in concentric circles, he then rapidly cooled the substance expecting the atoms to disarray, but again they arranged themselves in same fashion, representing the crystal pattern. He revised his observations and checked if they were twin crystals, but came up with the same observation. His experimental proof to Alan Mackay’s theoretical postulation (using Penrose mosaics ) explained the existence of quasicrystals. The discovery, opened the eyes of many crystallographers, who had dismissed their observations of higher fold symmetries as twin crystals. Today the applications of quasicrystals are found everywhere, from frying pans to LEDs and naturally occurring quasicrystals have also been reported. Had it not been Shechtman’s boldness to defy conventional wisdom, quasicrystals would never have been termed.
To these men of honour, I bow, their research work and experimental proofs that led to understanding of reality have extended our vision, lighted pathways for new discoveries, and truly grasped the essence of understanding existence.
For more information check out :: www.nobelprize.org